Why do dermatologists and skincare professionals recommend medical-grade skincare brands?

Medical-grade skincare brands are formulated with higher concentrations of active ingredients and are often supported by clinical research. These products are designed to target concerns like aging, discoloration, and texture more effectively than traditional over-the-counter skincare. At DermSilk, we focus on dermatologist-recommended brands that prioritize science-backed formulations and real results.

How do I choose the right professional skincare brand for my skin concerns?

The best professional skincare brand depends on your goals. Some brands specialize in anti-aging and collagen support, while others focus on hydration, pigmentation, or skin barrier repair. Look for products that match your primary concern and skin type, and consider starting with core essentials like a cleanser, treatment serum, and daily moisturizer. DermSilk offers a curated selection of clinically trusted brands so you can build a routine with confidence.

How can I tell if premium skincare products are authentic when shopping online?

Authentic professional skincare should always be purchased through authorized retailers. Buying from trusted providers helps ensure products are fresh, properly stored, and sourced directly from the brand. DermSilk partners directly with authorized manufacturers to provide genuine, professionally recommended skincare products so customers can shop with confidence.

What brands does DermSilk.com carry?

Plated Skin Science, Obagi, SkinMedica, iS Clinical, Sente, EltaMD, PCA Skin, Pavise, Hydrinity, Epicutis, Nutrafol, Epicuren Discovery, Allies of Skin, Augustinus Bader, IMAGE Skincare, ISDIN, Neocutis, Marini SkinSolutions (Formerly known as Jan Marini), Murad, NeoGenesis, Omnilux, Revision Skincare, SK-II, SkinBetter Science and ZO Skin Health.

ZO Skin Health Radical Night Repair

ZO Skin Health Radical Night Retinol (2 oz)

$194.00

Shipping calculated at checkout.

Qty:

Complete Your Purchase

Loading complementary products...

$110 ZO Skin Health Gift On Orders $399+

Free ($80 Value) ZO Skin Health Getting Skin Ready Kit *.

Receive a Free ($110 Value) ZO Skin Health Getting Skin Ready Kit * when you spend $399 or more on ZO Skin Health products. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.

[{"id":44807052558578,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"810866016103","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"ZO Skin Health Radical Night Retinol (2 oz)","public_title":null,"options":["Default Title"],"price":19400,"weight":2268,"compare_at_price":null,"inventory_management":"shopify","barcode":"810866016103","requires_selling_plan":false,"selling_plan_allocations":[{"price_adjustments":[{"position":1,"price":15520}],"price":15520,"compare_at_price":19400,"per_delivery_price":15520,"selling_plan_id":691929645422,"selling_plan_group_id":"299717bfa563a214e85ef514f0afad57df25e57f"},{"price_adjustments":[{"position":1,"price":15520}],"price":15520,"compare_at_price":19400,"per_delivery_price":15520,"selling_plan_id":691929678190,"selling_plan_group_id":"299717bfa563a214e85ef514f0afad57df25e57f"},{"price_adjustments":[{"position":1,"price":15520}],"price":15520,"compare_at_price":19400,"per_delivery_price":15520,"selling_plan_id":691929710958,"selling_plan_group_id":"299717bfa563a214e85ef514f0afad57df25e57f"},{"price_adjustments":[{"position":1,"price":15520}],"price":15520,"compare_at_price":19400,"per_delivery_price":15520,"selling_plan_id":691929743726,"selling_plan_group_id":"299717bfa563a214e85ef514f0afad57df25e57f"}],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Formulated with 1% retinol to help improve the appearance of skin texture, uneven pigmentation and fine lines and wrinkles. Please see below anticipated reactions and directions for use for this product.

Helps improve the appearance of skin’s brightness and provides a more even skin tone
Helps calm and soothe the skin
Helps minimize the appearance of fine lines and wrinkles

1% encapsulated retinol
Diminishes the appearance of fine lines + wrinkles while improving skin smoothness

Vitamins C, E and A
Provides additional antioxidant protection

Zanthoxylum bungeanum (sichuan pepper) fruit extract, sunflower seed oil and rosemary leaf extract
Minimizes the appearance of redness to restore a more youthful skin tone

Glycerin, sunflower seed oil, plukenetia volubilis seed oil
Hydrate and support the skin barrier with essential lipids

Directions

Radical Night Retinol is a high-potency retinol treatment. If you have not been using retinol, begin use gradually.

Following cleansing, apply to clean, dry skin twice a week
Increase frequency to alternate days
Then, increase use to every day as tolerated

Redness, flakiness, dryness, burning, or stinging are all normal, anticipated reactions when starting retinol. With regular product use, skin will acclimate, revealing a smoother, more even-toned and youthful-looking complexion. Pair your retinol with a ZO® functional hydrator to minimize anticipated reactions. Consult a physician for customized retinol protocol. Like prescription retinoic acid, retinol will make your skin more sensitive to the sun. Wear SPF 30 or higher daily.

Have questions on the recommended order to apply your ZO® products? Contact your local physician or use our live chat to speak to a ZO® Skincare Specialist for more information.

PM All Skin Types Anti-Aging TSA Approved

Cyclopentasiloxane, Dimethicone Crosspolymer, Dimethicone, Prunus Amygdalus Dulcis (Sweet Almond) Oleosomes, Aqua/Water/Eau, Glycerin, Polysorbate 20, Retinol, Plukenetia Volubilis Seed Oil, Helianthus Annus (Sunflower) Seed Oil, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Meristem Cell Culture, Zanthoxylum Bungeanum Fruit Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Zea Mays (Corn) Oil, Oleyl Alcohol, Lecithin, Diisopropyl Adipate, Tocopheryl Acetate, Ascorbyl Palmitate, Ascorbic Acid, Tocopherol, Sodium Sulfite, BHT, Beta-Carotene, Caprylyl Glycol, Fragrance (Parfum), Citral, Limonene, Phenoxyethanol, Chlorphenesin.

Free Samples (Choose One)

ZO Skin Health Radical Night Retinol (2 oz)

Complete Your Purchase

You may also like

$110 ZO Skin Health Gift On Orders $399+