Why do dermatologists and skincare professionals recommend medical-grade skincare brands?

Medical-grade skincare brands are formulated with higher concentrations of active ingredients and are often supported by clinical research. These products are designed to target concerns like aging, discoloration, and texture more effectively than traditional over-the-counter skincare. At DermSilk, we focus on dermatologist-recommended brands that prioritize science-backed formulations and real results.

How do I choose the right professional skincare brand for my skin concerns?

The best professional skincare brand depends on your goals. Some brands specialize in anti-aging and collagen support, while others focus on hydration, pigmentation, or skin barrier repair. Look for products that match your primary concern and skin type, and consider starting with core essentials like a cleanser, treatment serum, and daily moisturizer. DermSilk offers a curated selection of clinically trusted brands so you can build a routine with confidence.

How can I tell if premium skincare products are authentic when shopping online?

Authentic professional skincare should always be purchased through authorized retailers. Buying from trusted providers helps ensure products are fresh, properly stored, and sourced directly from the brand. DermSilk partners directly with authorized manufacturers to provide genuine, professionally recommended skincare products so customers can shop with confidence.

What brands does DermSilk.com carry?

Plated Skin Science, Obagi, SkinMedica, iS Clinical, Sente, EltaMD, PCA Skin, Pavise, Hydrinity, Epicutis, Nutrafol, Epicuren Discovery, Allies of Skin, Augustinus Bader, IMAGE Skincare, ISDIN, Neocutis, Marini SkinSolutions (Formerly known as Jan Marini), Murad, NeoGenesis, Omnilux, Revision Skincare, SK-II, SkinBetter Science and ZO Skin Health.

Antioxidant Protection

$20 iS Clinical Gift On Orders $249+

iS Clinical Cleansing Complex (6 oz)

$49

$20 iS Clinical Gift On Orders $249+

iS Clinical Pro-Heal Serum Advance+ (1 oz)

$177

$25 Obagi Gift On Orders $299+

Obagi Professional-C Serum 20% (1 fl oz)

$155

$20 iS Clinical Gift On Orders $249+

iS Clinical Reparative Moisture Emulsion (1.7 oz)

$116

$70 Revision Skincare Gift On Orders $299+

Revision Skincare C+ Correcting Complex 30%® (1 oz)

$190

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Intellishade® Original SPF 45 (1.7 oz)

$89

$20 iS Clinical Gift On Orders $249+

iS Clinical Hydra-Cool Serum (1 oz)

$108

$25 Obagi Gift On Orders $299+

Obagi Nu-Derm Toner (6.7 fl oz)

$55

$25 Obagi Gift On Orders $299+

Obagi Nu-Derm Foaming Gel (6.7 fl oz)

$55

$25 Obagi Gift On Orders $299+

Obagi Professional-C Serum 15% (1 fl oz)

$130

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Nectifirm® ADVANCED (1.7 oz)

$164

$70 Revision Skincare Gift On Orders $299+

Revision Skincare YouthFull Lip Replenisher® 0.33 oz

$44.50

$20 iS Clinical Gift On Orders $249+

iS Clinical Pro-Heal Serum Advance+ (0.5 oz)

$104

$40 SkinMedica Gift On Orders $399+

SkinMedica Retinol Complex 1.0 (1 oz)

$96

$70 Revision Skincare Gift On Orders $299+

Revision Skincare D·E·J Daily Boosting Serum™ (1 oz)

$230

$20 iS Clinical Gift On Orders $249+

iS Clinical Moisturizing Complex (1.7 oz)

$106

$40 SkinMedica Gift On Orders $399+

SkinMedica Vitamin C+E Complex (1 oz)

$106

$40 SkinMedica Gift On Orders $399+

SkinMedica Rejuvenative Moisturizer (2 oz)

$60

$148 ZO Skin Health Gift On Orders $399+

ZO Skin Health Daily Power Defense (1.7 oz)

$190

$20 iS Clinical Gift On Orders $249+

iS Clinical Cleansing Complex (2 oz)

$27

$20 iS Clinical Gift On Orders $249+

iS Clinical Youth Eye Complex (0.5 oz)

$125

$20 iS Clinical Gift On Orders $249+

iS Clinical Super Serum Advance+ (1 oz)

$177

$25 Obagi Gift On Orders $299+

Obagi-C C-Cleansing Gel (6 fl oz)

$50

$25 Obagi Gift On Orders $299+

Obagi-C C-Exfoliating Day Lotion (2 oz)

$90

$25 Obagi Gift On Orders $299+

Obagi-C Fx C-Clarifying Serum (1 fl oz)

$145

$70 Revision Skincare Gift On Orders $299+

Revision Skincare D·E·J Night Face Cream® (1.7 oz)

$190

$40 SkinMedica Gift On Orders $399+

SkinMedica Retinol Complex 0.5 (1 oz)

$80

$20 iS Clinical Gift On Orders $249+

iS Clinical Sheald Recovery Balm (2 oz)

$89

$20 iS Clinical Gift On Orders $249+

iS Clinical Copper Firming Mist (2.5 oz)

$45

$25 Obagi Gift On Orders $299+

Obagi Professional-C Microdermabrasion Polish + Mask (80 g)

$95

$148 ZO Skin Health Gift On Orders $399+

ZO Skin Health Gentle Cleanser All Skin Types (6.7 oz)

$50

$20 iS Clinical Gift On Orders $249+

iS Clinical Eye Complex (0.5 oz)

$98

$20 iS Clinical Gift On Orders $249+

iS Clinical Youth Complex (1 oz)

$172

$40 SkinMedica Gift On Orders $399+

SkinMedica Ultra Sheer Moisturizer (2 oz)

$60

$25 Obagi Gift On Orders $299+

Obagi Nu-Derm Exfoderm Forte (2 oz)

$105

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Intellishade® Matte SPF 45 (1.7 oz)

$89

$25 Obagi Gift On Orders $299+

Obagi-C C-Balancing Toner (6.7 fl oz)

$50

$40 SkinMedica Gift On Orders $399+

SkinMedica Retinol Complex 0.25 (1 oz)

$64

$20 iS Clinical Gift On Orders $249+

iS Clinical Hydra-Cool Serum (0.5 oz)

$70

$20 iS Clinical Gift On Orders $249+

iS Clinical Super Serum Advance+ (0.5 oz)

$104

$20 iS Clinical Gift On Orders $249+

iS Clinical Eclipse SPF50+ PerfectTint Beige (3.5 oz)

$54

SkinBetter Science Alto Advanced Defense and Repair Serum (1 oz)

$195

$20 iS Clinical Gift On Orders $249+

iS Clinical Youth Intensive Creme (1.7 oz)

$256

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Vitamin C Lotion 30% (1 oz)

$149

$40 SkinMedica Gift On Orders $399+

SkinMedica AHA/BHA Cream (2 oz)

$48

$25 Obagi Gift On Orders $299+

Obagi-C Fx C-Therapy Night Cream (2 oz)

$120

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Nectifirm® (1.7 oz)

$119

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Intellishade® Clear SPF 50 (1.7 oz)

$89

$25 Obagi Gift On Orders $299+

Obagi Nu-Derm Exfoderm (2 oz)

$105

SkinBetter Science AlphaRet Overnight Cream (1 oz)

$145

$20 iS Clinical Gift On Orders $249+

iS Clinical Eclipse SPF50+ (3.5 oz)

$54

$25 Obagi Gift On Orders $299+

Obagi Nu-Derm Fx System Normal to Dry

$525

ISDIN Photo Eryfotona Actinica Ultralight Emulsion Broad Spectrum SPF 50+ (3.4 oz).

ISDIN Photo Eryfotona Actinica Ultralight Emulsion Broad Spectrum... (3.4 oz)

$73

Hydrinity Restorative HA Serum (1 oz)

$120

SkinBetter Science EyeMax AlphaRet Overnight Cream (0.5 oz)

$135

$77 Neocutis Gift On Orders $349+

Neocutis ReACTIVE+ Anti-Oxidant Serum SPF 45 (1 oz)

$137

$20 iS Clinical Gift On Orders $249+

iS Clinical NeckPerfect Complex (1.7 oz)

$120

SkinBetter Science Alto Advanced Defense and Repair Serum (1.7 oz)

$275

$20 iS Clinical Gift On Orders $249+

iS Clinical Extreme Protect SPF 30 (3.5 oz)

$86

SkinBetter Science AlphaRet Overnight Cream (1.69 oz)

$210

SkinBetter Science Even Tone Correcting Serum (1.69 oz)

$170

Marini SkinSolutions C-ESTA Face Serum (1 oz)

$145

$25 Obagi Gift On Orders $299+

Obagi Professional-C Serum 20% (0.42 fl oz)

$85

ISDIN Photo Eryfotona Ageless Ultralight Emulsion Tinted Broad Spectrum SPF 50 (3.4 oz).

ISDIN Photo Eryfotona Ageless Ultralight Emulsion Tinted Broad Sp... (3.4 oz)

$78

$20 EltaMD Gift On Orders $199+

EltaMD Oil-In-Gel Cleanser (3.4 oz)

$37

SkinBetter Science InterFuse Treatment Cream Eye (0.5 oz)

$135

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Retinol Complete® 1.0 (1 oz)

$138

$20 iS Clinical Gift On Orders $249+

iS Clinical Pure Calm Collection

$219

$20 iS Clinical Gift On Orders $249+

iS Clinical Youth Serum (1 oz)

$174

$55 PCA Skin Gift On Orders $249+

PCA Skin C-Quench Antioxidant Serum (1 oz)

$135

$55 PCA Skin Gift On Orders $249+

PCA Skin C&E Advanced (1 oz)

$135

SkinBetter Science Intensive AlphaRet Overnight Cream (1.69 oz)

$210

SkinBetter Science Intensive AlphaRet Overnight Cream (1 oz)

$145

$70 Revision Skincare Gift On Orders $299+

Revision Skincare Tinted YouthFull Lip Replenisher® 0.33 oz

$46.50

$20 iS Clinical Gift On Orders $249+

iS Clinical Sheald Recovery Balm (0.5 oz)

$34

$148 ZO Skin Health Gift On Orders $399+

ZO Skin Health Firming Serum (1.6 oz)

$265

$20 iS Clinical Gift On Orders $249+

iS Clinical GeneXC Serum (1 oz)

$185

Epicutis Oil Cleanser (4 oz)

$85

$20 iS Clinical Gift On Orders $249+

iS Clinical LIProtect SPF 35 (0.17 oz)

$25

$25 Obagi Gift On Orders $299+

Obagi Nu-Derm Fx System Normal to Oily

$525

Free Samples (Choose One)

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$25 Obagi Gift On Orders $299+

$20 iS Clinical Gift On Orders $249+

$70 Revision Skincare Gift On Orders $299+

$70 Revision Skincare Gift On Orders $299+

$20 iS Clinical Gift On Orders $249+

$25 Obagi Gift On Orders $299+

$25 Obagi Gift On Orders $299+

$25 Obagi Gift On Orders $299+

$70 Revision Skincare Gift On Orders $299+

$70 Revision Skincare Gift On Orders $299+

$20 iS Clinical Gift On Orders $249+

$40 SkinMedica Gift On Orders $399+

$70 Revision Skincare Gift On Orders $299+

$20 iS Clinical Gift On Orders $249+

$40 SkinMedica Gift On Orders $399+

$40 SkinMedica Gift On Orders $399+

$148 ZO Skin Health Gift On Orders $399+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$25 Obagi Gift On Orders $299+

$25 Obagi Gift On Orders $299+

$25 Obagi Gift On Orders $299+

$70 Revision Skincare Gift On Orders $299+

$40 SkinMedica Gift On Orders $399+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$25 Obagi Gift On Orders $299+

$148 ZO Skin Health Gift On Orders $399+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$40 SkinMedica Gift On Orders $399+

$25 Obagi Gift On Orders $299+

$70 Revision Skincare Gift On Orders $299+

$25 Obagi Gift On Orders $299+

$40 SkinMedica Gift On Orders $399+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$70 Revision Skincare Gift On Orders $299+

$40 SkinMedica Gift On Orders $399+

$25 Obagi Gift On Orders $299+

$70 Revision Skincare Gift On Orders $299+

$70 Revision Skincare Gift On Orders $299+

$25 Obagi Gift On Orders $299+

$20 iS Clinical Gift On Orders $249+

$25 Obagi Gift On Orders $299+

$77 Neocutis Gift On Orders $349+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$25 Obagi Gift On Orders $299+

$20 EltaMD Gift On Orders $199+

$70 Revision Skincare Gift On Orders $299+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$55 PCA Skin Gift On Orders $249+

$55 PCA Skin Gift On Orders $249+

$70 Revision Skincare Gift On Orders $299+

$20 iS Clinical Gift On Orders $249+

$148 ZO Skin Health Gift On Orders $399+

$20 iS Clinical Gift On Orders $249+

$20 iS Clinical Gift On Orders $249+

$25 Obagi Gift On Orders $299+